Sinusoidal Obstruction Syndrome during oxaliplatin based chemotherapy treatment.
نویسندگان
چکیده
منابع مشابه
Sinusoidal obstruction syndrome after oxaliplatin-based chemotherapy
Drug-induced liver injury presents with extremely diverse histologic patterns, including necroinflammatory, cholestatic, steatotic and vascular patterns. Sinusoidal obstruction syndrome (SOS), also referred to as toxic sinusoidal injury, veno-occlusive disease or “blue liver syndrome”, is a commonly recognized vascular pattern of drug-induced liver injury, and has been frequently associated wit...
متن کاملfocal sinusoidal obstruction syndrome caused by oxaliplatin-induced chemotherapy: a case report
conclusions atypical irregular tumors should be considered as sos when the patient has received oxaliplatin-based chemotherapy. a qualitative imaging modality diagnosis, such as with diffusion-weighted mri, is superior to a morphological diagnosis in focal sos. this imaging modality can prevent unnecessary operations. case presentation a 40-year-old woman with rectal cancer underwent high anter...
متن کاملFocal Sinusoidal Obstruction Syndrome Caused by Oxaliplatin-Induced Chemotherapy: A Case Report
INTRODUCTION Sinusoidal obstruction syndrome (SOS) is a severe adverse event of long-term chemotherapy in patients with colorectal cancer. It usually develops as liver congestion due to diffuse microscopic obstruction in liver parenchyma. In contrast, it sometimes appears as a liver mass occurring with local parenchymal hemorrhaging, and is often misdiagnosed as liver metastasis. CASE PRESENT...
متن کاملSevere hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
BACKGROUND In advanced metastatic colorectal adenocarcinoma, the addition of a neo-adjuvant systemic treatment to surgery might translate into a survival advantage, although this is yet to be confirmed by ongoing randomized trials. The objective of this study was to assess the effects of preoperative systemic chemotherapy on the morphology of non-tumoral liver. PATIENTS AND METHODS A large se...
متن کاملvon Willebrand Factor-Rich Platelet Thrombi in the Liver Cause Sinusoidal Obstruction Syndrome following Oxaliplatin-Based Chemotherapy
Oxaliplatin-based chemotherapy is widely used to treat advanced colorectal cancer (CRC). Sinusoidal obstruction syndrome (SOS) due to oxaliplatin is a serious type of chemotherapy-associated liver injury (CALI) in CRC patients. SOS is thought to be caused by the sinusoidal endothelial cell damage, which results in the release of unusually-large von Willebrand factor multimers (UL-VWFMs) from en...
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ژورنال
عنوان ژورنال: Acta Oncologica Turcica
سال: 2018
ISSN: 0304-596X,2148-7669
DOI: 10.5505/aot.2018.63835